Inflatable door seal is installed in cold chain logistics overside port, which is used for insulation sealing between logistics overside port and truck. It is especially suitable for occasions the size of truck changes greatly. Pneumatic charging and discharging system are controlled by onebutton switch, which is convenient and quick to start. Effectively it prevents the cold air from entering the warm room or the hot air into the cold storage, which achieves energy saving. Inflatable door seals tightly surround the sides and roof of the van and have no effect on the opening of the doors. After loading and unloading, turn off the blower, under the action of the counterweight and the tensioning wire rope, the gas is discharged from the air bag rapidly. Subsequently the truck can leave quickly.